Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

C-geranyl compounds from Mimulus clevelandii

W R Phillips1, N J Baj, A A Gunatilaka

  • 1Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061-0212, USA.

Journal of Natural Products
|May 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: ROBIN: Reference observatory of basins for international hydrological climate change detection.

Scientific data·2025
Same author

ROBIN: Reference observatory of basins for international hydrological climate change detection.

Scientific data·2025
Same author

THE IMPACT OF CRISIS UPON THE BEHAVIOR OF NATIONS IN THE 1960's.

Multivariate behavioral research·2016
Same author

A new 1,2-deoxytaxane diterpenoid from Taxus chinensis.

Planta medica·2007
Same author

Physicians' opinions about partner notification methods: case reporting, patient referral, and provider referral.

Sexually transmitted infections·2004
Same author

Proposed active constituents of Dipladenia martiana.

Phytotherapy research : PTR·2001
Same journal

Polycyclic-Fused Cytochalasins with Anti-Liver Fibrosis Activity Produced by the Endophytic Fungus <i>Trichoderma harzianum</i>.

Journal of natural products·2026
Same journal

Oleraciamides A and B: Confirmation and Revision of Structures.

Journal of natural products·2026
Same journal

Synthesis and Stereochemical Revision of Violaceoid E, a Polyoxygenated Cyclohexanoid Natural Product Isolated from <i>Aspergillus violaceofuscus</i> Gasperini.

Journal of natural products·2026
Same journal

Cpumycins A-C, Aminated Benzoic Dimers from <i>Streptomyces</i> sp. CPU-W6, and Their Potential Cardioprotective Activities.

Journal of natural products·2026
Same journal

Editorial Introducing the Collection in Honor of Valerie J. Paul.

Journal of natural products·2026
Same journal

AI-Accelerated Structure Elucidation of Boavistamides A<b>-</b>C, Cyclic Depsipeptides from a Marine Filamentous Cyanobacterium Collected in Cabo Verde.

Journal of natural products·2026
See all related articles

Researchers isolated a new benzofuranone and five known geranylflavanones from Mimulus clevelandii. Advanced NMR techniques clarified structures and methylation sites for these natural products.

Area of Science:

  • Natural Product Chemistry
  • Organic Chemistry
  • Phytochemistry

Background:

  • Mimulus clevelandii is a plant species known for its potential chemical constituents.
  • Geranylflavanones are a class of natural products with diverse biological activities.
  • Structural elucidation of complex natural products often requires advanced spectroscopic methods.

Purpose of the Study:

  • To isolate and characterize novel and known compounds from the MeCOEt extract of Mimulus clevelandii.
  • To revise structural assignments for known geranylflavanones using advanced NMR techniques.
  • To resolve ambiguities regarding the methylation sites in related compounds.

Main Methods:

  • Extraction of plant material using methyl acetate (MeCOEt).
  • Fractionation of the crude extract to isolate individual compounds.

Related Experiment Videos

  • Structure elucidation using 2D Nuclear Magnetic Resonance (2D-NMR) spectroscopy.

    • Main Results:

    • Isolation of a novel compound, 4-geranyl-5-hydroxy-2(3H)-benzofuranone (1).
    • Identification of five known 6-geranylflavanones: diplacone (2a), 3'-O-methyldiplacone (2b), diplacol (2c), mimulone (2d), and 3'-O-methyldiplacol (2e).
    • Revision of structural assignments for diplacone and diplacol, and clarification of methylation sites in methyl ethers based on 2D-NMR data.

    Conclusions:

    • The study successfully identified a new benzofuranone derivative and confirmed the structures of several known geranylflavanones from Mimulus clevelandii.
    • Advanced NMR spectroscopy proved crucial for accurate structural determination and revision of existing assignments.
    • The findings contribute to the understanding of the phytochemical profile of Mimulus clevelandii and the structural diversity of geranylflavanones.