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Three new cytotoxic sesterterpenes from the marine sponge Hyrtios cf. erectus
G Ryu1, S Matsunaga, N Fusetani
1Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, University of Tokyo, Japan.
Journal of Natural Products
|May 1, 1996
Abstract:
Three new cytotoxic sesterterpenes, 1-3, have been isolated from the marine sponge Hyrtios cf. erectus. Their structures have been determined by interpretation of NMR data. They exhibited cytotoxicity against P-388 murine leukemia cells with IC50 values of 0.4-2.1 micrograms/mL.