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Early ovarian cancer: value of a negative staging laparotomy
W Faught1, R J Lotocki, M Heywood
1Department of Obstetrics, Gynecology and Reproductive Sciences, University of Manitoba Winnipeg, Canada.
Objective:
To assess the risk of recurrence in patients with stage I (negative cytology) epithelial ovarian cancer receiving no adjuvant therapy.
Methods:
Between 1976 and 1991, 51 patients with apparent stage I ovarian cancer underwent a comprehensive surgical staging that included: peritoneal cytology, omentectomy, pelvic and para-aortic lumphadenectomy, peritoneal biopsies and either unilateral salpingo-oophorectomy or TAH and BSO.
Results:
Eleven of 51 patients (22%) were found to have stage II or III disease based on a positive staging laparotomy. Thirty-seven of 40 patients with stage I disease received no further therapy. There was one recurrence (stage 1C - grade 1) in patients with surgical stage 1C while there were no recurrences in patients with either stage 1A or 1B disease.
Conclusion:
This study concludes that surgical staging in apparent early stage ovarian cancer can identify a group of patients that require surgical therapy alone.