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Giant intracranial aneurysms in two sisters: case report
1Department of Neurosurgery, Yamaguchi University, School of Medicine, Japan.
Surgical Neurology
|September 1, 1996
Summary
This report details two sisters with familial intracranial aneurysms presenting with cranial nerve palsy. Treatment involved internal carotid artery occlusion, successfully reducing aneurysm size.
Area of Science:
- Neurology
- Vascular Surgery
- Genetics
Background:
- Intracranial aneurysms rarely cause cranial nerve palsy due to mass effect.
- Familial clustering of intracranial aneurysms is uncommon.
Observation:
- Two sisters presented with identical giant internal carotid artery aneurysms in the cavernous portion.
- Both experienced ocular movement and facial sensory deficits from the aneurysms' space-occupying effect.
Findings:
- The siblings shared the same aneurysm location and familial predisposition.
- Proximal internal carotid artery occlusion promoted thrombosis and reduced aneurysm mass.
Implications:
- This is the first reported instance of siblings with bilateral giant internal carotid artery aneurysms.
- Highlights the importance of considering familial factors in aneurysm presentation and management.
- Demonstrates the efficacy of internal carotid artery occlusion for specific giant aneurysm types.