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Related Experiment Videos

Left-ventricular diastolic dysfunction during pneumonectomy--a transesophageal echocardiographic study

G Barletta1, M R Del Bene, A Palminiello

  • 1Department of Internal Medicine, University of Florence, Italy.

The Thoracic and Cardiovascular Surgeon
|April 1, 1996
PubMed
Summary

Pneumonectomy can cause temporary left ventricular diastolic dysfunction and mitral regurgitation due to right ventricular overload, impacting cardiac chamber geometry. These effects resolve before chest closure.

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Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Echocardiography

Background:

  • Pneumonectomy can lead to acute increases in pulmonary capillary pressure.
  • Left-ventricular dysfunction may unexpectedly develop post-pneumonectomy.
  • Morphofunctional cardiac changes after pneumonectomy require investigation.

Purpose of the Study:

  • To investigate the morphofunctional modifications in left cardiac chambers after pneumonectomy.
  • To assess the impact of pneumonectomy on interventricular septum geometry and left ventricular function.
  • To identify transient cardiac changes induced by pneumonectomy.

Main Methods:

  • Intraoperative transesophageal echocardiography (TEE) in 8 patients undergoing pneumonectomy.
  • Analysis of interventricular septum movement and geometry.

Related Experiment Videos

  • Evaluation of pulmonary vein flow-profile and mitral regurgitation using Doppler and color Doppler.

    • Main Results:

    • Pneumonectomy induced rectilinear changes in the interventricular septum geometry, linked to increased right-ventricular dimensions.
    • Pulmonary vein flow showed increased turbulence, with altered systolic components and mild mitral regurgitation.
    • These echocardiographic changes were transient and resolved before chest closure.
    • No significant alteration in left-ventricular systolic function was observed.

    Conclusions:

    • Acute right-ventricular overload following pneumonectomy alters interventricular septum geometry.
    • This geometric change induces transient left-ventricular diastolic dysfunction and mild mitral regurgitation.
    • These cardiac effects are temporary and reversible after pneumonectomy.