Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Composite grafts for critical ischaemia

F Benedetti-Valentini1, B Gossetti, I Irace

  • 1La Sapienza, University of Rome, Italy.

Cardiovascular Surgery (London, England)
|June 1, 1996
PubMed
Summary

Composite grafts, combining autogenous vein and polytetrafluoroethylene (PTFE) prosthesis, show comparable patency to saphenous veins for lower limb bypass surgery. These composite grafts offer a viable alternative when autogenous veins are insufficient.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of self-expanding vascular stent in superior vena cava syndrome for advanced tumours.

Annals of the Royal College of Surgeons of England·2021
Same author

Open and endovascular treatment by covered and multilayer stents in the therapy of renal artery aneurysms: mid and long term outcomes in a single center experience.

Il Giornale di chirurgia·2017
Same author

Surgical Management of a Ruptured Basilic Vein Aneurysm.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2016
Same author

Focus on the prophylaxis, epidemiology and therapy of methicillin-resistant Staphylococcus aureus surgical site infections and a position paper on associated risk factors: the perspective of an Italian group of surgeons.

World journal of emergency surgery : WJES·2016
Same author

Flow-mediated dilation benefits of mesoglycan in peripheral artery disease.

International angiology : a journal of the International Union of Angiology·2015
Same author

Renal Stenting for Kidney Salvage in the Management of Renal Artery Atherosclerotic Stenosis.

Angiology·2014

Area of Science:

  • Vascular Surgery
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Critical limb ischemia necessitates bypass surgery to restore blood flow.
  • Autogenous saphenous veins and polytetrafluoroethylene (PTFE) grafts are common bypass materials.
  • Limitations exist for using autogenous veins exclusively in complex bypass procedures.

Purpose of the Study:

  • To compare the long-term patency of composite grafts versus autogenous saphenous veins and PTFE grafts.
  • To evaluate the efficacy of composite grafts in femoropopliteal and femorotibial bypasses for critical limb ischemia.
  • To determine the optimal graft material when autogenous vein availability is limited.

Main Methods:

  • A retrospective analysis of 236 femoropopliteal and 64 femorotibial bypasses.

Related Experiment Videos

  • Comparison of graft patency rates among composite grafts (n=29), autogenous saphenous veins (n=189), and PTFE grafts (n=82).
  • Composite grafts consisted of a distal autogenous vein segment anastomosed to a proximal PTFE prosthesis, with specific considerations for grafts crossing the knee joint.

    • Main Results:

    • No early occlusions were observed in composite grafts.
    • At a mean follow-up of 4 years, patency rates were: autogenous saphenous vein 81.2%, PTFE 67.1%, and composite grafts 76%.
    • Composite grafts demonstrated no significant difference in patency compared to autogenous saphenous veins and were significantly superior to PTFE grafts.

    Conclusions:

    • Composite grafts serve as an effective alternative to autogenous saphenous veins when the latter are unavailable for the entire bypass length.
    • The comparable patency of composite and autogenous vein grafts supports their use in complex lower limb revascularization.
    • These findings advocate for the consideration of composite grafts in vascular reconstruction for critical limb ischemia.