Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparing antiepileptic drugs

A G Marson1, D Chadwick

  • 1Walton Centre for Neurology and Neurosurgery, Liverpool, UK.

Current Opinion in Neurology
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Choosing antiepileptic drugs requires strong evidence. This review examines randomized trials comparing monotherapy treatments, highlighting current knowledge gaps and future research needs for epilepsy management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accelerated long-term forgetting in people with newly diagnosed focal epilepsy.

Epilepsy & behavior : E&B·2026
Same author

HIV testing in primary care in a low-prevalence area of Northeast England.

HIV medicine·2025
Same author

British HIV Association guidelines on the management of opportunistic infection in people living with HIV: Considerations in pregnancy 2024.

HIV medicine·2024
Same author

Safe provision of elective endocrine surgery operations amid the COVID-19 crisis.

Annals of the Royal College of Surgeons of England·2021
Same author

Using routinely recorded data in a UK RCT: a comparison to standard prospective data collection methods.

Trials·2021
Same author

Author response: Post-thyroidectomy bleeding: analysis of risk factors from a national registry.

The British journal of surgery·2021
Same journal

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Current opinion in neurology·2026
Same journal

Editorial introduction.

Current opinion in neurology·2026
Same journal

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same journal

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches.

Current opinion in neurology·2026
Same journal

Dystonia: from phenotypes to genetics and therapeutic advances.

Current opinion in neurology·2026
Same journal

What can we learn from eye movements in movement disorders and Parkinson's disease?

Current opinion in neurology·2026
See all related articles

Area of Science:

  • Neurology
  • Pharmacology
  • Clinical Trials

Background:

  • Physician decision-making for antiepileptic drug (AED) selection relies on robust evidence.
  • Existing evidence primarily stems from randomized, controlled monotherapy trials.

Purpose of the Study:

  • To review the current evidence base for AED selection in epilepsy.
  • To focus on recent randomized trials comparing different AED monotherapies.
  • To identify limitations in current knowledge and propose future research directions.

Main Methods:

  • Analysis of evidence from randomized, controlled monotherapy trials.
  • Focus on four recently published trials comparing monotherapy with different AEDs.

Main Results:

Related Experiment Videos

  • Discussion of evidence from comparative monotherapy trials.
  • Identification of limitations in the current body of evidence for AED selection.

Conclusions:

  • Emphasizes the need for evidence-based selection of antiepileptic drugs.
  • Highlights areas where further research is required to guide clinical practice in epilepsy treatment.