Resistive loaded breathing changes the motor drive to arm and leg muscles in man

Breathing through inspiratory or expiratory resistive loads activates respiratory afferents. In healthy individuals, we explored the recruitment of motor units in arm (adductor pollicis, AP and biceps branchialis, BB) and leg (vastus lateralis, VL) muscle groups during voluntary contractions sustained at 80% of maximal force. Quantitative EMG analysis consisted of measurement of energies in high (EH) and low (EL) frequency bands. EH and EL changes were measured at constant time, i.e. 10 and 20 s after the onset of plateau contraction. The resistive load was added to the inspiratory or the expiratory circuit for 10-min periods. Its value was high but not enough to induce changes in blood gases and blood pressure. Compared to muscle contractions performed during non-loaded breathing periods, inspiratory loading did not affect BB and VL contractions, whereas it induced significant changes in AP contraction, characterized by enhanced variations in EL value measured at 10 s. Expiratory loading affected solely the VP contraction. Then, EH decreased at 10 and 20 s while it increased always when VP contractions were executed during non-loaded breathing. Expiratory loading elevated the functional residual capacity (FRC), but the load-induced changes in VL contraction persisted when subjects adjusted their FRC to the control level. These data suggest that respiratory afferents influence the skeleto-motor drive. Thus, viscero-somatic reflex may be present in patients with severe obstructive pulmonary disease.