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The pattern of acute renal failure in Kelantan

D Zainal1, C S Loo

  • 1Department of Medicine, University Science Malaysia Hospital, Kubang Kerian, Kelantan, Malaysia.

Singapore Medical Journal
|February 1, 1996
PubMed

Insights

This study on acute renal failure (ARF) found that most patients had non-oliguric ARF. Early recognition and careful use of nephrotoxic drugs can reduce ARF incidence and severity.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Clinical Research

Background:

  • Acute renal failure (ARF) management has evolved with diagnostic and therapeutic advancements.
  • Understanding ARF presentation, management, and areas for improvement is crucial.

Purpose of the Study:

  • To analyze the presentation, management, and outcomes of acute renal failure in adult patients.
  • To identify factors influencing ARF severity and mortality.
  • To suggest strategies for reducing ARF incidence and severity.

Main Methods:

  • Retrospective study of 164 adult patients admitted between June 1986 and December 1989.
  • Analysis of patient demographics, aetiologies of ARF, and treatment modalities.
  • Comparison of outcomes between oliguric and non-oliguric ARF patients.

Main Results:

  • The study included 164 patients (61.6% male, 38.4% female) with a mean age of 49.8 years.
  • 80% of patients presented with non-oliguric acute renal failure.
  • Oliguric ARF was associated with higher mortality and increased need for dialysis.

Conclusions:

  • Early recognition of acute renal failure is vital for better patient outcomes.
  • Judicious use of nephrotoxic drugs can help prevent or mitigate ARF.
  • Further research and improved clinical practices can decrease the incidence and severity of ARF.

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