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The pattern of acute renal failure in Kelantan
1Department of Medicine, University Science Malaysia Hospital, Kubang Kerian, Kelantan, Malaysia.
Insights
This study on acute renal failure (ARF) found that most patients had non-oliguric ARF. Early recognition and careful use of nephrotoxic drugs can reduce ARF incidence and severity.
Area of Science:
- Nephrology
- Internal Medicine
- Clinical Research
Background:
- Acute renal failure (ARF) management has evolved with diagnostic and therapeutic advancements.
- Understanding ARF presentation, management, and areas for improvement is crucial.
Purpose of the Study:
- To analyze the presentation, management, and outcomes of acute renal failure in adult patients.
- To identify factors influencing ARF severity and mortality.
- To suggest strategies for reducing ARF incidence and severity.
Main Methods:
- Retrospective study of 164 adult patients admitted between June 1986 and December 1989.
- Analysis of patient demographics, aetiologies of ARF, and treatment modalities.
- Comparison of outcomes between oliguric and non-oliguric ARF patients.
Main Results:
- The study included 164 patients (61.6% male, 38.4% female) with a mean age of 49.8 years.
- 80% of patients presented with non-oliguric acute renal failure.
- Oliguric ARF was associated with higher mortality and increased need for dialysis.
Conclusions:
- Early recognition of acute renal failure is vital for better patient outcomes.
- Judicious use of nephrotoxic drugs can help prevent or mitigate ARF.
- Further research and improved clinical practices can decrease the incidence and severity of ARF.
Abstract:
Acute renal failure (ARF) has undergone many changes with advances both in diagnosis and therapy. A retrospective study covering three and a half years from June 1986 to December 1989 of adults admitted to Hospital of the University of Science Malaysia examined the various aspects of presentation of the syndrome, management and areas where improvement can be made. A total of 164 patients were included in the study. 61.6% were male and 38.4% were female. The mean age was 49.8 +/- 17.2 years with 70% of patients being more than 40 years old. The aetiologies of acute renal failure were analysed and discussed. The majority of the patients (80%) had non-oliguric acute renal failure. Oliguric acute renal failure patients have higher mortality and more frequently need dialysis. Early recognition of acute renal failure and discerning use of nephrotoxic drugs could result in decrease in incidence and severity of renal failure.