Gastric leiomyosarcoma associated with hypoglycemia in a dog

Hypoglycemia associated with a large, gastric leiomyosarcoma was diagnosed in an 11-year-old, yellow Labrador retriever. The dog had persistent hypoglycemia and low serum insulin levels. Although radiological and ultrasonographical evaluations suggested an abdominal mass involving the liver, a large, nonresectable, gastric mass was found during exploratory laparotomy. Metastasis was not identified on gross inspection of the liver or abdomen, and no metastatic lesions were seen on thoracic radiographs. The dog was euthanized. Histopathological examination of the mass revealed a poorly differentiated, gastric leiomyosarcoma that extended into the mesentery without regional lymph-node involvement.