Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Kidney changes in experimental obesity]

W H Peters, G Hegewald, K Brachmann

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |April 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Urinary GSTP1-1 excretion is markedly increased in normotensive pregnancy as well as in preeclampsia.

    Journal of nephrology·2005
    Same author

    Expression profiling of colon cancer cell lines and colon biopsies: towards a screening system for potential cancer-preventive compounds.

    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)·2005
    Same author

    Glutathione S-transferases P1-1 and A1-1 in ovarian cyst fluids.

    European journal of gynaecological oncology·2002
    Same author

    Paternal contribution to the risk for pre-eclampsia.

    Journal of medical genetics·2002
    Same author

    Neutrophil oxygen radical production in pre-eclampsia with HELLP syndrome.

    European journal of obstetrics, gynecology, and reproductive biology·2002
    Same author

    The glutathione biotransformation system and colorectal cancer risk in humans.

    Scandinavian journal of gastroenterology. Supplement·2002

    Diet-induced obesity in rats did not significantly alter plasma proteins or urea-nitrogen levels. While creatinine levels were mostly stable, some obese rats showed temporary increases, with no observed kidney abnormalities.

    Area of Science:

    • Nephrology
    • Metabolic Disorders
    • Animal Models

    Context:

    • Obesity is linked to various health complications, including potential renal changes.
    • Understanding these renal alterations in obesity is crucial for managing associated health risks.
    • Experimental models provide valuable insights into the physiological effects of obesity.

    Purpose:

    • To investigate the biochemical and morphological renal changes in a rat model of dietary-induced obesity.
    • To compare renal function markers and kidney structures in obese versus control rats.
    • To assess the impact of long-term high-fat diet feeding on kidney health.

    Summary:

    • Obese rats fed a high-fat diet exhibited normal plasma protein and urea-nitrogen concentrations.
    • Mean creatinine levels remained unchanged between obese and control groups, though dynamic phase obesity showed some elevated creatinine values.

    Related Experiment Videos

  • Histological examination revealed no pathological abnormalities in the renal structures or blood vessels of obese rats.
  • Impact:

    • This study suggests that short-term dietary-induced obesity in rats may not cause significant renal pathology.
    • Findings contribute to the understanding of kidney function under conditions of obesity.
    • Highlights the importance of considering dynamic changes in renal markers during obesity studies.