Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Objective analysis of centromere separation

G Mèhes1, A Tàrnok, L Pajor

  • 1Department of Pathology, University Medical School of Pècs, Hungary.

Human Genetics
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fecal expression of Escherichia coli lysine decarboxylase (LdcC) is downregulated in E-cadherin negative lobular breast carcinoma.

Physiology international·2020
Same author

Apocrine Gland-Rich Skin Has a Non-Inflammatory IL-17-Related Immune Milieu, that Turns to Inflammatory IL-17-Mediated Disease in Hidradenitis Suppurativa.

The Journal of investigative dermatology·2018
Same author

Conserved hierarchical gain of chromosome 4 is an independent prognostic factor in high hyperdiploid pediatric acute lymphoblastic leukemia.

Leukemia research·2016
Same author

Cytometry in the brain: studying differentiation to diagnostic applications in brain disease and regeneration therapy.

Cell proliferation·2014
Same author

New insights into cell cycle and DNA damage response machineries through high-resolution AMICO quantitative imaging cytometry.

Cell proliferation·2013
Same author

Correlation among metallothionein expression, intratumoural macrophage infiltration and the risk of metastasis in human cutaneous malignant melanoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2012
Same journal

AI in variant analysis: fast track to genetic diagnoses.

Human genetics·2026
Same journal

Combined family-based association and linkage analyses in families affected by attention-deficit hyperactivity disorder.

Human genetics·2026
Same journal

Investigating the shared genetic architecture between selective immunoglobulin A deficiency and autoimmune diseases.

Human genetics·2026
Same journal

ARHI as a key regulator of EMT and metastasis in pancreatic cancer via the Notch-1 pathway.

Human genetics·2026
Same journal

Large-scale mitogenome analysis reveals complex maternal genetic connections between Sino-Tibetan- and Altaic-speaking populations.

Human genetics·2026
Same journal

Correction: A comprehensive and accessible model for co-segregation analysis in BRCA1, BRCA2, and PALB2 variant classification.

Human genetics·2026
See all related articles

Centromere separation and premature division are critical but hard to study. A new computerized image analysis system offers objective and exact staging of centromere division, improving research accuracy.

Area of Science:

  • Cell Biology
  • Genetics
  • Microscopy

Background:

  • Centromere separation and premature centromere division are crucial events in cell division.
  • Current methods for studying these processes are often subjective and lack precision.

Purpose of the Study:

  • To develop and validate a simple computerized image analysis system for objective staging of centromere division.
  • To overcome the limitations of existing subjective and inaccurate investigation methods.

Main Methods:

  • Development of a computerized image analysis system.
  • Application of the system to analyze centromere division in cellular samples.
  • Objective staging of centromere division based on quantitative image analysis.

Main Results:

Related Experiment Videos

  • The computerized system enables objective and exact staging of centromere division.
  • Demonstrated improved accuracy and reduced subjectivity in assessing centromere division.
  • Provided a reliable tool for quantitative analysis of centromere dynamics.

Conclusions:

  • The developed image analysis system provides a robust and objective method for studying centromere division.
  • This advancement facilitates more accurate research into cell cycle regulation and chromosome segregation.
  • The system has the potential to significantly improve the investigation of disorders related to abnormal centromere function.