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Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1)
T Tanaka1, J Inazawa, Y Nakamura
1Laboratory of Molecular Medicine, Institute of Medical Science, University of Tokyo, Japan.
Genomics
|February 15, 1996
Abstract:
We have isolated a human cDNA encoding a protein of 334 amino acids that shows 96% identity in amino acid sequence to murine cytosolic malate dehydrogenase. Heart and skeletal muscle expressed this gene most highly among the adult human tissues examined by Northern blot analysis. By fluorescence in situ hybridization, we determined its chromosomal location to be 2p15.