Segregation and linkage analysis of the complex trait Q1
Related Experiment Video
Updated: Oct 13, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
Published on: February 3, 2013
L D Atwood1, B D Mitchell, N C Stowell
1Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147, USA.
Abstract:
Segregation and linkage analysis of GAW9 Problem 2 quantitative trait 1 (Q1) was performed. Eight segregation models comprising all possible combinations of the environmental factor (EF), quantitative trait 2 (Q2), and quantitative trait 3 (Q3) as covariates were considered. Seven of the eight segregation models showed strong evidence for a major gene, the other model was marginal. When all genotypes are known, some evidence for linkage (lod > 2) was found to all three of the markers that affect Q1. Furthermore, four of the eight models each showed some linkage (lod > 2) to two of the three markers that affect Q1 with no false positives. Each of these segregation analysis major genes is a hybrid combination of the true multiple loci that affect Q1.
More Related Videos
Related Concept Videos
Dihybrid Crosses
Law of Segregation
Law of Independent Assortment
Dihybrid Crosses
Law of Independent Assortment
Epistasis Analysis

