A graphical approach for presenting linkage results from a genomic screen
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E W Pugh1, D M Mandal, A F Wilson
1Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, USA.
Genetic Epidemiology
|January 1, 1995
Abstract:
Initially, a sib-pair linkage analysis was performed between the marker loci and six untransformed variables. Results from several variations of this initial analysis were compared using a graphical approach (P-plots) to simplify presentation. When results were compared to the generating model, most of the aspects of the generating model were recovered, although we did not find evidence of the polygenic component shared by Q2 and Q3, or evidence of linkage between MG4 and Q4 at the 0.01 level.