[Interrelation of endogenous intoxication and immunodepression in the pathogenesis of craniocerebral trauma]

Endogenous intoxication degree as well as immunodepression level were examined in 50 patients with brain contusion of moderate and severe degree of gravity. Uncomplicated course of disease was observed in 20 patients while the complicated one--in 21 individuals. 9 patients with unfavourable outcome were also observed. The complex of biochemical and immunological studies of blood was used many times in the course of traumatic disease. The peculiarities of endogenous intoxication alterations as well as of T-lymphocytes system were revealed in acute period of craniocerebral trauma. The data obtained may be used in prognosis of both disease current and complications development.