[Autonomic regulation of the cardiovascular system in patients with schizoaffective psychosis]

A comparative analysis of R-R intervals distribution parameters in ECG histograms (modal value, moda amplitude, variation range) in 60 healthy individuals as well as in 35 patients with schizoaffective disorders (ICD-10: F 25.1) was performed. These ECG parameters reflected sympathic and parasympathic influences of vegetative nervous system on the cardiac rhythm. Histograms of RR-intervals distribution parameters had been significantly changed in patients during schizoaffective symptoms development as compared to control group: modal value was shifted toward short interval area, moda amplitude was rised, variation range was narrowed. It means the increasing sympathic influence and decreasing parasympathic nervous system activity. The alternation trend was the same in patients with the prevalence of affective symptoms (affectdominant form of schizoaffective psychosis) or with paranoid predominance (schizodominant form of schizoaffective psychosis). The intensity of these changes was more expressed in patients with affectdominant form of schizoaffective psychosis.