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Non-cardiac chest pain: a real clinical problem
1Department of Gastroenterology, S. Orsola Hospital, Bologna, Italy.
Non-cardiac chest pain is common, often stemming from esophageal issues like gastro-oesophageal reflux disease, rather than heart problems. Accurate diagnosis and patient perception impact outcomes for this frequent clinical concern.
Area of Science:
- Gastroenterology
- Cardiology
- Clinical Medicine
Background:
- Non-cardiac chest pain is a prevalent clinical challenge.
- A significant percentage of patients undergoing arteriography for suspected cardiac pain have normal coronary arteries.
- Gastro-oesophageal reflux disease is a primary cause of esophageal chest pain, accounting for up to 60% of cases.
Purpose of the Study:
- To highlight the frequency of non-cardiac chest pain.
- To emphasize the role of esophageal dysfunction, particularly gastro-oesophageal reflux disease, in non-cardiac chest pain.
- To underscore the diagnostic complexity and prognostic factors in non-cardiac chest pain.
Main Methods:
- Review of clinical presentations of non-cardiac chest pain.
- Analysis of diagnostic work-up for patients with chest pain.
- Evaluation of etiological factors, focusing on esophageal sources.
Main Results:
- 10-50% of patients with anginal pain symptoms show normal coronary arteries upon arteriography.
- Up to 60% of non-cardiac chest pain cases are attributed to esophageal origins, predominantly gastro-oesophageal reflux disease.
- Excluding cardiac disease and identifying esophageal causes can necessitate extensive investigations.
Conclusions:
- Non-cardiac chest pain is frequently linked to esophageal conditions, especially gastro-oesophageal reflux disease.
- A thorough diagnostic process is crucial for differentiating cardiac from non-cardiac chest pain.
- Patient outcomes are influenced by the specific diagnosis and their subjective experience of symptoms.
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