An extraction method for determination of benzene in tissue by gas chromatography

An extraction procedure has been developed for the determination of benzene by gas chromatography in tissues following inhalation. Results are reproducible using very small quanities of sample (0.05 g for tissue and 0.02 ml for blood). The procedure has been applied to the analysis of blood and tissue of A.K.R. mice following a single exposure to levels similar to those that may be found in industrial hygiene atmospheres.