Related Experiment Videos
Clonal hematopoiesis and acquired thalassemia in common variable immunodeficiency
M Belickova1, H W Schroeder, Y L Guan
1Prague Institute of Hematology, Czech Republic.
Molecular Medicine (Cambridge, Mass.)
|November 1, 1994
Summary
Common variable immunodeficiency (CVID) patients can develop acquired thalassemia, indicated by abnormal globin synthesis. This suggests a potential stem cell defect contributing to both conditions.
Area of Science:
- Immunology
- Hematology
- Genetics
Background:
- Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia and recurrent infections.
- The genetic basis for CVID remains largely unidentified.