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Mice as models of human developmental disorders: natural and artificial mutants
1Department of Anatomy and Developmental Biology, University College London, UK. uogasda@ucl.ac.uk
Current Opinion in Genetics & Development
|June 1, 1996
Abstract:
Over the past year, the mouse has been used as a model to make significant contributions towards our understanding of human developmental disorders. The existence of both natural and artificial mouse mutants has not only facilitated the identification of mutations and provided candidate genes for human disorders but has also increased our knowledge regarding the cellular and molecular processes involved in normal mammalian embryogenesis.
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