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Updated: Aug 10, 2026

Dissection and Staining of Drosophila Larval Ovaries
Published on: May 13, 2011
RNA localization and the development of asymmetry during Drosophila oogenesis
1Wellcome/CRC Institute and The Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK.
Abstract:
Recent work on axis formation in Drosophila has revealed that polarity arises in several distinct stages during oogenesis. One cell of a germline cyst is selected to become the oocyte, the position of the oocyte determines the posterior of the follicle, and the position of the oocyte nucleus determines the dorsal side. Each of these symmetry-breaking steps involves the asymmetric localization of a unique structure, leading to polarization of the cytoskeleton and the localization of specific mRNAs.
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