Use of tolbutamide as a substrate probe for human hepatic cytochrome P450 2C9

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Haemodynamic effects of parenteral vs. enteral paracetamol in critically ill patients: a randomised controlled trial.

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Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis.

Archives of biochemistry and biophysics·2007

The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7.

Drug metabolism and disposition: the biological fate of chemicals·2006

Electrochemical characterisation of the human cytochrome P450 CYP2C9.

Biochemical pharmacology·2005

Towards integrated ADME prediction: past, present and future directions for modelling metabolism by UDP-glucuronosyltransferases.

Journal of molecular graphics & modelling·2004

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Methods in enzymology·2026

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Methods in enzymology·2026

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Methods in enzymology·2026

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Methods in enzymology·2026

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Methods in enzymology·2026

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Methods in enzymology·2026

Delta-9-tetrahydrocannabinol alleviates inflammation by modulating immune responses in LPS-induced murine inflammation model.

Frontiers in immunology·2026

Charge-screening dominates signal transduction in electrochemical nucleic acid sensors for aminoglycosides.

bioRxiv : the preprint server for biology·2026

Dissociation kinetics and avidity gate SARS-CoV-2 neutralization by HR2 stem helix antibodies.

bioRxiv : the preprint server for biology·2026

De novo design of protease-activatable cytokine prodrugs.

bioRxiv : the preprint server for biology·2026

Hopeaphenol targets histidine kinase signaling across kingdoms to suppress bacterial virulence and potentiate plant immunity.

bioRxiv : the preprint server for biology·2026

Antidiabetic and Hepatoprotective Effects of Dried Custard Apple (Annona squamosa) Pulp in Streptozotocin-Nicotinamide-Induced Diabetic Rats.

Molecular nutrition & food research·2026

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Use of tolbutamide as a substrate probe for human hepatic cytochrome P450 2C9

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The Role of the Kidney in Drug Elimination: Transport, Metabolism, and the Impact of Kidney Disease on Drug Clearance.

Haemodynamic effects of parenteral vs. enteral paracetamol in critically ill patients: a randomised controlled trial.

Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis.

The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7.

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Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

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Use of tolbutamide as a substrate probe for human hepatic cytochrome P450 2C9

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