Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Posttraumatic olfactory dysfunction: MR and clinical evaluation

D M Yousem¹, R J Geckle, W B Bilker

¹Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.

AJNR. American Journal of Neuroradiology

|June 1, 1996

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Functional connectivity differences of the olfactory network in Parkinson's Disease, mild cognitive impairment and cognitively normal individuals: A resting-state fMRI study.

Neuroscience·2024

Same author

Does Gadolinium Deposition Lead to Metabolite Alteration in the Dentate Nucleus? An MRS Study in Patients with MS.

AJNR. American journal of neuroradiology·2022

Same author

2018-2022 Radiology Residency and Neuroradiology Fellowship Match Data: Preferences and Success Rates of Applicants.

AJNR. American journal of neuroradiology·2022

Same author

Value of Emergent Neurovascular Imaging for "Seat Belt Injury": A Multi-institutional Study.

AJNR. American journal of neuroradiology·2021

Same author

Radiologically Isolated Syndrome: A Review for Neuroradiologists.

AJNR. American journal of neuroradiology·2020

Same author

Parental Leave and Neuroradiology Fellowships.

AJNR. American journal of neuroradiology·2020

Magnetic Resonance Imaging (MRI) reveals high rates of injury in the olfactory bulbs and tracts in patients with post-traumatic smell loss. Damage sites often don

Area of Science:

Neurology
Radiology
Otolaryngology

Background:

Post-traumatic olfactory deficits are common following head injuries.
Understanding the anatomical correlates of smell dysfunction is crucial for diagnosis and management.

Purpose of the Study:

To identify the specific sites of injury in patients experiencing olfactory deficits after trauma.
To correlate imaging findings with clinical olfactory test results.

Main Methods:

Twenty-five patients with post-traumatic olfactory dysfunction underwent olfactory testing, endoscopy, and MR imaging.
MR scans focused on olfactory bulbs, tracts, and temporal lobes, with quantitative and qualitative damage assessments.
Correlations were drawn between imaging data and odor identification, detection, memory, and discrimination test scores.

Related Experiment Videos

Main Results:

88% of patients showed injuries to olfactory bulbs and tracts; 60% had subfrontal region damage; 32% had temporal lobe damage.
While injuries were prevalent, correlations between specific damage sites and olfactory test scores were weak.
Patients with complete smell loss exhibited greater volume reduction in olfactory bulbs and tracts compared to those with residual smell function.

Conclusions:

MR imaging demonstrates a high incidence (88%) of abnormalities in patients with post-traumatic olfactory dysfunction.
Injuries are predominantly located in the olfactory bulbs, tracts, and inferior frontal lobes.
The lack of strong correlation may stem from multifocal injuries, primary olfactory nerve damage, and sample size limitations.