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MR in trichloroethane poisoning

M del Amo1, J Berenguer, T Pujol

  • 1Department of Neuroradiology, Hospital Clinic i provincial de Barcelona Spain.

AJNR. American Journal of Neuroradiology
|June 1, 1996
PubMed
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Acute trichloroethane poisoning from typewriter correction fluid caused brain lesions. Imaging revealed damage in the basal ganglia and cortex, similar to methanol and carbon monoxide poisoning.

Area of Science:

  • Toxicology
  • Neurology
  • Radiology

Background:

  • Trichloroethane compounds are industrial solvents with known neurotoxic potential.
  • Inhalation is a common route of occupational and accidental exposure.
  • Typewriter correction fluid is a potential source of volatile solvent exposure.

Observation:

  • A case of acute trichloroethane intoxication is presented.
  • The patient experienced symptoms following inhalation of typewriter correction fluid.
  • Cerebral lesions were identified in the basal ganglia and cortex.

Findings:

  • Computed tomography (CT) and magnetic resonance (MR) imaging were utilized.
  • Lesions observed were comparable to those seen in methanol and carbon monoxide poisoning.

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  • This suggests a shared mechanism of neurotoxicity affecting specific brain regions.

    • Implications:

    • Highlights the neurotoxic risks associated with common household/office products.
    • Emphasizes the importance of recognizing imaging similarities between different toxic encephalopathies.
    • Suggests potential diagnostic and therapeutic parallels for trichloroethane, methanol, and carbon monoxide poisoning.