Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insulin action in man

A J Scheen1, P J Lefèbvre

  • 1Department of Medicine, CHU Liège, Belgium.

Diabetes & Metabolism
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Insulin action regulates glucose metabolism by controlling liver glucose production and storage in tissues. Understanding cellular insulin action improves treatment for insulin resistance and non-insulin-dependent diabetes mellitus.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Sitagliptine (Januvia): incretin enhancer potentiating insulin secretion for the treatment of type 2 diabetes].

Revue medicale de Liege·2008
Same author

[Medication of the month. Rimonabant (Acomplia): first CB1 receptor antagonist of the endocannabinoid system].

Revue medicale de Liege·2008
Same author

[Isolated tricuspid valve endocarditis as a cause of fever of unknown origin].

Revue medicale de Liege·2008
Same author

[A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge].

Revue medicale de Liege·2008
Same author

[Therapy of type 2 diabetes: between insulin sensitizers and insulin secreting agents].

Revue medicale de Liege·2008
Same author

[Aspirin resistance in diabetic patients: laboratory entity or clinical reality?].

Revue medicale de Liege·2007
Same journal

Glucagon-like peptide-1 receptor agonists and risk of pancreaticobiliary cancers in patients with type 2 diabetes: a nationwide cohort study.

Diabetes & metabolism·2026
Same journal

Decreased risk of new-onset osteoporosis in patients with Type 2 diabetes on SGLT-2 inhibitors.

Diabetes & metabolism·2026
Same journal

Two faces of autoimmune hyperinsulinemia: contrasting type B insulin resistance syndrome and exogenous insulin antibody syndrome.

Diabetes & metabolism·2026
Same journal

CGM-based metrics and mortality in older adults living with type 2 diabetes on insulin therapy: a secondary analysis of the HYPOAGE study.

Diabetes & metabolism·2026
Same journal

Persistent burden and management gaps of hypoglycemia in pediatric type 1 diabetes: insights from the Epi-GLUREDIA Study.

Diabetes & metabolism·2026
Same journal

Blood oxygen saturation and its associations with autonomic and peripheral neuropathy in diabetes.

Diabetes & metabolism·2026
See all related articles

Area of Science:

  • Endocrinology
  • Metabolic Regulation
  • Physiology

Background:

  • Insulin is vital for glucose metabolism, regulating hepatic glucose production and peripheral glucose uptake.
  • Insulin resistance is a key factor in non-insulin-dependent diabetes mellitus and associated with atherosclerotic risk factors.

Purpose of the Study:

  • To review the mechanisms of insulin action and methods for its assessment.
  • To highlight advancements in understanding cellular insulin action and its implications for disease treatment.

Main Methods:

  • Review of in vivo methods to assess insulin action in liver and muscle.
  • Discussion of open-loop and closed-loop approaches for evaluating insulin effects.
  • Consideration of preceptor, receptor, and postreceptor levels of insulin action.

Related Experiment Videos

Main Results:

  • Significant progress in understanding cellular insulin action over the past decade.
  • Identification of preceptor, receptor, and postreceptor levels as critical sites affected in insulin resistance.
  • Improved comprehension of the pathophysiology of non-insulin-dependent diabetes mellitus.

Conclusions:

  • Enhanced understanding of insulin action offers new therapeutic strategies for insulin resistance.
  • Advances in knowledge improve the approach to managing non-insulin-dependent diabetes mellitus.
  • Targeting cellular insulin action pathways holds promise for treating metabolic and cardiovascular risk factors.