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Echovirus type 23 observed as a nosocomial infection in infants
1Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.
Insights
Echovirus type 23 was detected in young children with chronic conditions, often presenting with gastrointestinal or respiratory symptoms. This study highlights its less frequent occurrence compared to Echovirus type 22.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Public Health
Background:
- Echoviruses are known pathogens causing various clinical manifestations in children.
- Understanding the epidemiology and clinical features of specific echovirus types is crucial for public health surveillance.
- Echovirus type 23 has been less frequently reported compared to other enteroviruses.
Purpose of the Study:
- To report the isolation and clinical features of Echovirus type 23 in hospitalized children.
- To compare the occurrence of Echovirus type 23 with Echovirus type 22 during the study period.
Main Methods:
- Retrospective analysis of viral isolates from pediatric patients.
- Sample collection included fecal and nasopharyngeal specimens.
- Clinical data and patient demographics were reviewed.
Main Results:
- Echovirus type 23 was isolated from 5 children (aged 1-13 months) over a multi-decade study period.
- The virus was detected in fecal samples (4 cases) associated with diarrhea/vomiting and nasopharyngeal secretions (1 case) with respiratory symptoms.
- Echovirus type 23 infections were observed to be less common than Echovirus type 22.
Conclusions:
- Echovirus type 23 can cause gastrointestinal and respiratory illness in infants and young children.
- The lower incidence of Echovirus type 23 warrants further epidemiological investigation.
- Clinical presentation of Echovirus type 23 resembles that of Echovirus type 22.
Abstract:
Echovirus type 23 was isolated from 5 children, aged 1-13 months, during a 7-month period, covering a study period of several decades. The children were hospitalized for long periods because of chronic conditions. In 4 cases the virus was isolated from faecal samples, collected because of diarrhoea and/or vomiting. In one case echovirus type 23 was collected from nasopharyngeal secretions from a child with respiratory symptoms. The features of echovirus type 23 infection were similar to those of echovirus type 22, but it is striking that infections with echovirus type 23 were less common during the same decades covered by the study.