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Tolypodiol, an antiinflammatory diterpenoid from the cyanobacterium Tolypothrix nodosa
M R Prinsep1, R A Thomson, M L West
1Department of Chemistry, University of Waikato, Hamilton, New Zealand. michele@waikato.ac.nz
Journal of Natural Products
|August 1, 1996
Abstract:
A new diterpenoid, tolypodiol (1), has been isolated from the terrestrial cyanobacterium Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The monoacetate derivative 2 was prepared. Tolypodiol (1) and its monoacetate derivative 2 show potent antiinflammatory activity in the mouse ear edema assay.