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Gender and affect in schizophrenia

D Addington1, J Addington, S Patten

  • 1Department of Psychiatry, University of Calgary, Alberta, Canada.

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|June 1, 1996
PubMed
Summary
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This study found no significant gender differences in negative or depressive symptoms among individuals with schizophrenia. The research did not support the hypothesis that males experience more negative symptoms and females experience more depressive symptoms.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Previous research on gender differences in schizophrenia symptoms has yielded inconsistent results.
  • Limitations in prior studies include retrospective designs and inadequate assessment tools.

Purpose of the Study:

  • To investigate gender-based differences in negative and depressive symptoms in schizophrenia.
  • To test the hypothesis that males with schizophrenia exhibit more negative symptoms and females exhibit more depressive symptoms.

Main Methods:

  • 113 inpatients diagnosed with schizophrenia (45 female, 68 male) were assessed.
  • Symptoms were measured using the Positive and Negative Syndrome Scale (PANSS) for negative symptoms and the Calgary Depression Scale for Schizophrenia (CDSS) for depressive symptoms.

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  • A subset of 92 participants was reassessed after 3 months.

    • Main Results:

    • No statistically significant differences were observed in the levels of negative symptoms between males and females.
    • No statistically significant differences were observed in the levels of depressive symptoms between males and females.

    Conclusions:

    • The study's findings do not support the hypothesis of sex-based disparities in negative or depressive symptoms within the schizophrenia population.
    • Further research is warranted to explore potential contributing factors to symptom presentation in schizophrenia, independent of gender.