HMG-CoA reductase inhibitors: role in normal and malignant cells

Tumor cell survival dependence on the DHX9 DExH-box helicase.

Oncogene·2016

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

Oncogene·2014

Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells.

Oncogene·2014

SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.

Oncogene·2013

Requirement for isoprenoid-dependent posttranslational modifications in the cell-cycle progression of human breast-cancer cells.

International journal of oncology·2011

Factors released from human breast-cancer cells counteract the inhibitory effects of mevinolin on DNA-synthesis and morphology but not on hmg coa reductase-activity.

International journal of oncology·2011

Breast Cancer Treatment in Patients with Tuberculosis: Challenges and Therapeutic Considerations.

Critical reviews in oncology/hematology·2026

Time-varying prognostic value of circulating tumor DNA in urothelial carcinoma: a systematic review and reconstructed patient-data meta-analysis.

Critical reviews in oncology/hematology·2026

TIL Therapy in Relapsed/Refractory Neuroblastoma: A Translational Roadmap from Immunobiology to Early-Phase Trials.

Critical reviews in oncology/hematology·2026

Prognostic Models and Predictors of Recurrence in Resectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis.

Critical reviews in oncology/hematology·2026

Molecular Mechanisms of Exosome-Mediated Drug Resistance in Central Nervous System Tumours.

Critical reviews in oncology/hematology·2026

Immunological consequences of mesenchymal stem cell therapy in HPV-driven cervical cancer: A systematic review and stratification framework.

Critical reviews in oncology/hematology·2026

Silencing GJB2 attenuates IL-1β-induced chondrocyte injury by activating Nrf2/HO-1 signaling and preserving mitochondrial function.

Folia histochemica et cytobiologica·2026

DPM2 promotes melanoma progression and serves as a prognostic factor.

Melanoma research·2026

Efficacy of combined atorvastatin and paromomycin in treating experimental cryptosporidiosis in immunosuppressed mice.

QJM : monthly journal of the Association of Physicians·2026

Pan-RAS Inhibitor Shows Activity in Advanced Lung Cancer.

Cancer discovery·2026

Purine nucleoside phosphorylase in breast cancer from metabolic regulation to targeted therapy: challenges and opportunities.

RSC medicinal chemistry·2026

Yifeixiaoji decoction as an adjunct to osimertinib therapy in advanced EGFR-mutated NSCLC: protocol for a randomized, double-blind, placebo-controlled trial.

Frontiers in medicine·2026

Related Experiment Videos

HMG-CoA reductase inhibitors: role in normal and malignant cells

Related Concept Videos

Tumor cell survival dependence on the DHX9 DExH-box helicase.

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells.

SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.

Requirement for isoprenoid-dependent posttranslational modifications in the cell-cycle progression of human breast-cancer cells.

Factors released from human breast-cancer cells counteract the inhibitory effects of mevinolin on DNA-synthesis and morphology but not on hmg coa reductase-activity.

Breast Cancer Treatment in Patients with Tuberculosis: Challenges and Therapeutic Considerations.

Time-varying prognostic value of circulating tumor DNA in urothelial carcinoma: a systematic review and reconstructed patient-data meta-analysis.

TIL Therapy in Relapsed/Refractory Neuroblastoma: A Translational Roadmap from Immunobiology to Early-Phase Trials.

Prognostic Models and Predictors of Recurrence in Resectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis.

Molecular Mechanisms of Exosome-Mediated Drug Resistance in Central Nervous System Tumours.

Immunological consequences of mesenchymal stem cell therapy in HPV-driven cervical cancer: A systematic review and stratification framework.

Silencing GJB2 attenuates IL-1β-induced chondrocyte injury by activating Nrf2/HO-1 signaling and preserving mitochondrial function.

DPM2 promotes melanoma progression and serves as a prognostic factor.

Efficacy of combined atorvastatin and paromomycin in treating experimental cryptosporidiosis in immunosuppressed mice.

Pan-RAS Inhibitor Shows Activity in Advanced Lung Cancer.

Purine nucleoside phosphorylase in breast cancer from metabolic regulation to targeted therapy: challenges and opportunities.

Yifeixiaoji decoction as an adjunct to osimertinib therapy in advanced EGFR-mutated NSCLC: protocol for a randomized, double-blind, placebo-controlled trial.

Related Experiment Videos

HMG-CoA reductase inhibitors: role in normal and malignant cells

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