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Immune response to mouse mammary tumour virus
1Ludwig Institute of Cancer Research, Lausanne Branch, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland. sluther@eliot.unil.ch
Current Opinion in Immunology
|August 1, 1996
Abstract:
Superantigens of mouse mammary tumor virus induce a strong cognate interaction between T cells and B cells. In addition to amplifying the virus-infected B-cell pool, this superantigen-driven interaction leads to the differentiation of virus-specific B cells into plasma cells. Successful interaction between T cells and B cells is required for completion of the viral life cycle.