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Related Experiment Videos

[Risperidone-induced priapism]

S Maizel1, L Umansky, H Y Knobler

  • 1Eitanim Psychiatric Center, Jerusalem.

Harefuah
|June 2, 1996
PubMed
Summary
This summary is machine-generated.

Priapism, a prolonged erection, is a rare side effect of psychotropic medications like risperidone due to alpha-adrenergic blockade. This case highlights the importance of monitoring for this adverse effect in patients prescribed risperidone.

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Area of Science:

  • Pharmacology
  • Urology
  • Psychiatry

Background:

  • Priapism is a prolonged erection, a rare adverse effect of psychotropic medications.
  • This condition is often linked to alpha-adrenergic receptor blockade.
  • Risperidone is a novel antipsychotic medication.

Observation:

  • A case of priapism in a 44-year-old male patient receiving risperidone is described.
  • The patient experienced urinary retention, which was managed with catheterization and saline irrigations.
  • Priapism resolved after surgical evacuation of a penile hematoma.

Findings:

  • This report may represent the first documented instance of priapism solely associated with risperidone use.
  • Previous reports have involved patients taking multiple psychotropic medications concurrently.

Related Experiment Videos

  • The mechanism is attributed to alpha-adrenergic receptor blockade by risperidone.

    • Implications:

    • Clinicians should be vigilant for priapism in patients treated with risperidone.
    • Early recognition and management of priapism are crucial.
    • This case underscores the potential for risperidone monotherapy to induce priapism.