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Related Experiment Videos

Selenium: a quest for better understanding

V Badmaev1, M Majeed, R A Passwater

  • 1Sabinsa Corporation, Piscataway, NJ, USA.

Alternative Therapies in Health and Medicine
|July 1, 1996
PubMed
Summary
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Selenium is a vital trace element for human health, crucial for antioxidant defense, immune function, and more. Supplementation, particularly with L-(+)-selenomethionine, supports these functions, with ongoing research into higher doses for specific conditions.

Area of Science:

  • Nutritional Science
  • Biochemistry
  • Human Health

Background:

  • Selenium is an essential trace element vital for human nutrition and disease prevention.
  • Low selenium status is linked to increased risks of cardiovascular disease and various cancers.
  • Selenium plays a role in antioxidant defense, thyroid hormone function, and immune system activity.

Purpose of the Study:

  • To review the essential role of selenium in human health.
  • To discuss the implications of selenium status on disease risks.
  • To explore the function of selenoproteins and the use of selenium supplementation.

Main Methods:

  • Review of epidemiological studies and scientific literature.
  • Analysis of the biological functions of selenium and selenoproteins.

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  • Discussion of selenium supplementation forms and dosage recommendations.

    • Main Results:

    • Selenium is critical for antioxidant defense, immune function, sperm formation, and prostate health.
    • L-(+)-selenomethionine is a safe and effective form of selenium supplementation.
    • Nutritional doses range from 50-200 micrograms/day, with pharmacological doses considered for active conditions.

    Conclusions:

    • Adequate selenium intake is essential for preventing disease and maintaining overall health.
    • Selenium supplementation can support critical bodily functions.
    • Further research is exploring higher selenium doses for therapeutic applications.