Predicting cardiorespiratory fitness without exercise testing in epidemiologic studies: a concurrent validity study
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Updated: Nov 4, 2026

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
Published on: February 2, 2024
1Division of HPR, Wayne State University, Detroit, MI 48202, USA.
Abstract:
Maximal oxygen consumption (VO2 max) is the criterion measure of cardiorespiratory fitness. However, because it has traditionally been regarded as a costly, labor-intense measure to obtain, VO2 max assessment has seen only limited use in epidemiological studies. Recently, methods for predicting VO2 max have been developed that rely on a combination of self-report variables. The purpose of this study was to determine the relationship of two multivariable equations for estimating VO2 max in a sample of 123 females (M age = 38.8 + 8.4 yrs.). In one equation a seven-item physical activity index was used and in the other equation a single physical activity question was used. The between-formula relationship for predicted VO2 max values was significant (r = 0.80, p < 0.0001). Predicted VO2 max values were also positively related with other indices of physical activity (rs = 0.26 to 0.74). Preliminary results suggest there is a high degree of correlation between the two equations studied, as well as other indices of physical activity. These formulas may be of interest to epidemiologists in situations where direct methods of VO2 max assessment are not feasible.
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