Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Crystalline lens parameters in infancy

I C Wood1, D O Mutti, K Zadnik

  • 1Department of Optometry, University of Manchester Institute of Science and Technology, UK.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

KvSNP: accurately predicting the effect of genetic variants in voltage-gated potassium channels.

Bioinformatics (Oxford, England)·2011
Same author

Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study: methods and findings to date.

Contact lens & anterior eye : the journal of the British Contact Lens Association·2007
Same author

Multiple chromatin modifications important for gene expression changes in cardiac hypertrophy.

Biochemical Society transactions·2006
Same author

The relation between disease asymmetry and severity in keratoconus.

The British journal of ophthalmology·2004
Same author

Dominant-negative subunits reveal potassium channel families that contribute to M-like potassium currents.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2002
Same author

Visual acuity in contact lens wearers.

Optometry and vision science : official publication of the American Academy of Optometry·2001
Same journal

Mesopic Illumination in Natural Environments: Implications for Myopia Research.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Axial Length Growth Reference Curves and LMS Parameters for Japanese Children and Adolescents Aged 4-20 Years: The TMM BirThree Cohort Study.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Effect of Switching Myopia Control Strategies on Axial Elongation in Children with Poor Response to Highly Aspherical Lenslet Therapy.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Quantifying the Role of Longitudinal Chromatic Aberration and Age in Night Vision Disturbances.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Impaired Rod-Mediated Vision is the Functional Hallmark of Ageing and Early and Intermediate Age-Related Macular Degeneration.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Analytical Performance, Spatial Dynamics and Clinically Meaningful Change Thresholds for Automated Non-invasive Tear Film Assessment Using the Oculus Keratograph 5M.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
See all related articles

Infant crystalline lens power is crucial for eye development. This study found lens refractive index decreases with age, impacting overall lens power more than surface curvature changes.

Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Ocular Development

Background:

  • Infant crystalline lens parameters are vital for ocular development but poorly documented.
  • Understanding these parameters is key to identifying refractive errors and developmental trajectories.

Purpose of the Study:

  • To measure infant crystalline lens parameters, including radii of curvature and equivalent refractive index.
  • To investigate the relationship between these parameters and age-related changes in refractive error.
  • To assess the role of videophakometry in infant eye research.

Main Methods:

  • Measured lens and corneal radii of curvature using a video-based keratophakometry in 19 infants (3-18 months).
  • Determined refractive error via cycloplegic retinoscopy.

Related Experiment Videos

  • Calculated equivalent refractive index using established ocular dimensions.

    • Main Results:

    • Median refractive error was +1.50 D; median corneal power was 43.5 D.
    • Infant lens radii of curvature were flatter than standard schematic eye values.
    • A significant reduction in hyperopia with age was observed (r = -0.47, P = 0.043).
    • Lens equivalent refractive index (1.49) was higher than previously reported values.
    • No age-related trends in lens or corneal radii were found.

    Conclusions:

    • The crystalline lens undergoes changes in equivalent refractive index, not surface curvature, during early childhood.
    • Videophakometry is a viable method for studying infant crystalline lens parameters and their role in ocular development.
    • Age-related decreases in lens power are primarily driven by declining refractive index.