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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
MR of disc protrusion engendered by infectious spondylitis
J R Jinkins1, C Bazan, L Xiong
1Department of Radiology, University of Texas Health Science Center at San Antonio 78284-7800, USA.
Purpose:
The purpose of this study was to determine if infection-related disc protrusion formed a component of the perispinous/epidural mass in patients with intervertebral disc infection.
Method:
A retrospective review was undertaken of 16 consecutive patients with intervertebral disc space infection who were referred for gadolinium-enhanced MRI. Possible correlation was sought between disc infection and the presence of associated posterior disc protrusion as determined by MRI.
Results:
Of the 16 infected discs, 10 cases were in the lumbosacral spine, 3 in the thoracic spine, and 3 in the cervical spine. Four cases had isolated posteriorly directed disc protrusion, and 12 showed both posterior and anterior disc protrusions. The infection in patients with disc protrusion was related to Staphylococcus aureus in 14 patients, Salmonella enteritidis in 1, and Streptococcus pneumoniae in 1.
Conclusion:
This study showed that disc protrusion occurred in combination with disc space infections. Local factors such as the secretion by hyaluronidase from Staphylococcus aureus may play an important role in causing focal disc protrusion. The clinical importance of this finding is in the recognition that a significant part of the compromise of the spinal canal in cases of disc infection can be related to disc fragments engendered by the infectious process.
Insights
Intervertebral disc infection can cause disc protrusion, leading to spinal canal compromise. Staphylococcus aureus is a common cause, potentially secreting hyaluronidase to facilitate protrusion.
Area of Science:
- Spinal imaging
- Infectious diseases
- Neurosurgery
Background:
- Intervertebral disc infections can lead to significant spinal pathology.
- The formation of perispinous or epidural masses is a concern in disc infections.
Purpose of the Study:
- To investigate whether infection-related disc protrusion is a component of epidural masses in patients with intervertebral disc infection.
- To explore the correlation between disc infection and posterior disc protrusion.
Main Methods:
- Retrospective review of 16 consecutive patients with intervertebral disc space infection.
- Gadolinium-enhanced MRI was used to assess disc protrusion and spinal canal compromise.
Main Results:
- Disc protrusion was observed in combination with disc space infections.
- 12 out of 16 patients showed both posterior and anterior disc protrusions.
- Staphylococcus aureus was the most common pathogen identified (14 patients).
Conclusions:
- Disc protrusion is a significant factor in spinal canal compromise during disc infections.
- Bacterial factors, like hyaluronidase from Staphylococcus aureus, may contribute to focal disc protrusion.
- Recognizing infection-related disc fragments is crucial for managing spinal canal compromise.
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