Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development of gastrointestinal functions

O Koldovský1, M Dobiásová, P Hahn

  • 1Department of Pediatrics, University of Arizona College of Medicine, Tucson, USA.

Physiological Research
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microbiota affects the expression of genes involved in HPA axis regulation and local metabolism of glucocorticoids in chronic psychosocial stress.

Brain, behavior, and immunity·2018
Same author

Cellular differentiation of non-transformed intestinal epithelial cells is regulated by Lactobacillus rhamnosus and L. casei strains.

Physiological research·2018
Same author

Atherogenic impact of lecithin-cholesterol acyltransferase and its relation to cholesterol esterification rate in HDL (FER(HDL)) and AIP [log(TG/HDL-C)] biomarkers: the butterfly effect?

Physiological research·2017
Same author

Peripheral circadian clocks are diversely affected by adrenalectomy.

Chronobiology international·2016
Same author

Biomarkers of cardiometabolic risk in obese/overweight children: effect of lifestyle intervention.

Physiological research·2014
Same author

Distinct effect of stress on 11beta-hydroxysteroid dehydrogenase type 1 and corticosteroid receptors in dorsal and ventral hippocampus.

Physiological research·2014
Same journal

Effects of THC, CBD, and Their Combination on EEG Dynamics in Rats.

Physiological research·2026
Same journal

Prophylactic Effect of Echinacoside on PIPN by Inhibiting Spinal Neuroinflammation and Exerting Neuroprotective Effects.

Physiological research·2026
Same journal

Comparison of Motor Learning Abilities Using Balance Training in Young and Senior Women.

Physiological research·2026
Same journal

The Role of NAT10-Mediated ac4C Modification in Osteoblast Function and Bone Formation: Insights from Integrative Bioinformatics and Experimental Validation.

Physiological research·2026
Same journal

Challenges and Solutions in Low-Biomass Respiratory Microbiome Profiling: A Workflow for Bronchoalveolar Lavage Fluid Sequencing in Guinea Pigs.

Physiological research·2026
Same journal

Sodium Selenite Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension by Upregulating GPX3 and Ameliorating Vascular Remodeling.

Physiological research·2026
See all related articles

Mammalian perinatal development shows significant changes in nutrient digestion and absorption. Key findings include higher triglyceride absorption in suckling rats and developmental shifts in intestinal function, influenced by hormones.

Area of Science:

  • Gastroenterology
  • Developmental Biology
  • Physiology

Background:

  • Mammalian perinatal development involves complex adaptations in nutrient digestion and absorption.
  • Understanding these changes is crucial for infant nutrition and health.
  • Hormonal influences, particularly from the adrenal cortex and thyroid gland, play a significant role.

Purpose of the Study:

  • To summarize data on carbohydrate, lipid, and protein digestion and absorption during mammalian perinatal development.
  • To review developmental changes in intestinal segment specialization.
  • To highlight the maturative effects of hormones on the developing gastrointestinal tract.

Main Methods:

  • Review of existing studies on perinatal gastrointestinal development in mammals, including human fetuses.

Related Experiment Videos

  • Analysis of data on nutrient absorption, carnitine content, gluconeogenesis, ketone production, and colonic transport.
  • Examination of the influence of adrenal cortex and thyroid hormones.

    • Main Results:

    • Triglyceride absorption is 2-3 times higher in suckling rats compared to adults, correlating with high fat intake.
    • Postnatal decrease in rat small intestinal carnitine content, reaching adult levels at weaning.
    • Evidence suggests neonatal small intestinal gluconeogenesis and ketone production from long-chain fatty acids in infant rats.
    • Developing rat colon shows ileum-like characteristics in the proximal region early postnatally.
    • Hormonal factors significantly impact intestinal maturation.

    Conclusions:

    • Significant developmental changes occur in nutrient absorption and intestinal function during the perinatal period.
    • The developing gastrointestinal tract exhibits unique physiological characteristics adapted for neonatal nutrition.
    • Hormonal regulation is a critical determinant of intestinal maturation and specialization.