Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nutritional support after hepatic resection: a randomized prospective study

T Nishizaki1, K Takenaka, K Yanaga

  • 1Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

Hepato-Gastroenterology
|May 1, 1996
PubMed
Summary

Nutritional support with dextrose after major liver surgery improves patient nutritional status and may preserve muscle. This study suggests the remnant liver can effectively utilize dextrose for energy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical outcomes of carbon-ion radiotherapy for residual or recurrent hepatocellular carcinoma after transarterial chemoembolization.

ESMO gastrointestinal oncology·2026
Same author

A change in the timing for starting systemic therapies for hepatocellular carcinoma: the comparison of sorafenib and lenvatinib as the first-line treatment.

Acta gastro-enterologica Belgica·2021
Same author

Impact of muscle volume loss on acute oral mucositis in patients undergoing concurrent chemoradiotherapy after oral cancer resection.

International journal of oral and maxillofacial surgery·2021
Same author

Right hepatic venous system variation in living donors: a three-dimensional CT analysis.

The British journal of surgery·2020
Same author

Functional Analysis of Human Hepatocytes Isolated From Chimeric Mouse Liver.

Transplantation proceedings·2018
Same author

Clinical Outcomes of Living Liver Transplantation According to the Presence of Sarcopenia as Defined by Skeletal Muscle Mass, Hand Grip, and Gait Speed.

Transplantation proceedings·2017

Area of Science:

  • Hepatobiliary surgery
  • Metabolic adaptation
  • Nutritional support

Background:

  • Consensus is lacking on dextrose use post-hepatectomy in chronic liver disease due to altered remnant liver metabolism.
  • Remnant liver metabolism shifts from glucose to fatty acid utilization after hepatectomy.
  • Investigating nutritional support benefits in patients with cirrhosis or chronic hepatitis undergoing major hepatectomy.

Purpose of the Study:

  • To determine the efficacy of nutritional support using dextrose in patients following major hepatectomy.
  • To assess the impact of nutritional intervention on metabolic status and protein preservation.

Main Methods:

  • 19 patients underwent major hepatectomy.
  • 10 patients received peripheral dextrose (10 kcal/kg/day) for seven days.

Related Experiment Videos

  • 9 patients received hypertonic glucose, with average non-protein caloric intake of 20 and 30 kcal/kg/day, respectively.

    • Main Results:

    • Nutritional support led to improved retinol binding protein and prealbumin levels.
    • Urinary 3-methylhistidine excretion decreased, indicating reduced muscle protein breakdown.
    • Nitrogen balance normalized earlier in the nutritional support group compared to conventional methods.

    Conclusions:

    • The remnant liver is capable of utilizing dextrose effectively.
    • Nutritional support post-hepatectomy significantly improves nutritional status.
    • Nutritional support may play a role in preserving muscle protein mass in these patients.