Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

First and second trimester sonography: an American perspective

W E Scorza1, A Vintzileos

  • 1Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, USA.

International Journal of Fertility and Menopausal Studies
|May 1, 1996
PubMed
Summary

Ultrasound effectively dates pregnancies and detects fetal aneuploidy and intrauterine growth restriction (IUGR). Specific measurements like crown-rump length and nuchal translucency aid in early detection and risk assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is manual palpation of the uterine scar following vaginal birth after cesarean section (VBAC) helpful?

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2014
Same author

Cesarean scar pregnancy is a precursor of morbidly adherent placenta.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2014
Same author

Three-dimensional sonographic diagnosis of vasa previa.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2004
Same author

Recurrent uterine rupture after abdominal pregnancy.

The Journal of maternal-fetal medicine·2002
Same author

Appropriateness of antibiotic use in the postpartum period.

The Journal of maternal-fetal medicine·2001
Same author

Defining the relationship between obstetricians and maternal-fetal medicine specialists.

American journal of obstetrics and gynecology·2001

Area of Science:

  • Maternal-Fetal Medicine
  • Diagnostic Imaging
  • Prenatal Diagnostics

Background:

  • First- and second-trimester ultrasonography is crucial in the US for gestational dating, detecting fetal aneuploidy, identifying intrauterine growth restriction (IUGR), and assessing cervical incompetence.
  • Crown-rump length (CRL) is the most accurate first-trimester dating parameter (7-12 weeks).
  • Second-trimester biometry, including biparietal diameter, head circumference, transverse cerebellar diameter (TCD), abdominal circumference, and long bone lengths, aids in assessment.

Purpose of the Study:

  • To review the applications of first- and second-trimester ultrasonography in prenatal diagnostics.
  • To highlight ultrasound's role in identifying fetal aneuploidy and IUGR.
  • To present a model for adjusting trisomy 21 risk using ultrasound and other markers.

Related Experiment Videos

Main Methods:

  • Utilizing established ultrasound parameters for gestational dating (CRL, biparietal diameter, etc.).
  • Assessing fetal biometry and structural anomalies for aneuploidy detection (cystic hygroma, nuchal translucency, nuchal fold, long bone length).
  • Employing estimated fetal weight (FFW) curves for IUGR and trisomy detection, and evaluating transvaginal ultrasound for cervical incompetence.

Main Results:

  • First-trimester CRL is optimal for dating. Second-trimester TCD is relatively spared in IUGR.
  • Ultrasound identifies aneuploidy markers like cystic hygroma and nuchal translucency. Short long bones (30% sensitivity) and increased nuchal fold (34% sensitivity for Down syndrome) indicate aneuploidy risk.
  • FFW curves detect IUGR and trisomy 18 (60% sensitivity), but not trisomy 21 (8-12% sensitivity). A combined model improves trisomy 21 risk assessment.
  • Transvaginal ultrasound and transfundal pressure aid in diagnosing cervical incompetence.

Conclusions:

  • Ultrasonography is a versatile tool in prenatal care, essential for dating, aneuploidy screening, IUGR detection, and cervical competence assessment.
  • Specific ultrasound markers and biometric measurements significantly contribute to identifying fetuses at risk for aneuploidy and growth restriction.
  • Integrating ultrasound findings with maternal age and biochemical screening enhances the accuracy of risk assessment for conditions like Down syndrome.