Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events

EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion.

The Journal of cell biology·2001

Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role for beta4 tyrosines 1422 and 1440 in hemidesmosome assembly.

The Journal of biological chemistry·2001

Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle.

Molecular cell·2001

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling.

The Journal of clinical investigation·2000

Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.

The Journal of biological chemistry·2000

Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.

The Journal of biological chemistry·2000

Atypical PI3Ks coordinate chemotaxis, signaling dynamics, and multicellular development in Dictyostelium.

Journal of cell science·2026

Targeted ATAC-see (tATAC-see): A visual assay for target-specific chromatin profiling.

Journal of cell science·2026

Fine-tuning integrin adhesion, trafficking and signalling through post-translational modification.

Journal of cell science·2026

Dynamic micropatterning uncovers spatial dynamics of B cell immune synapse formation.

Journal of cell science·2026

A 3D printable device for non-invasive longitudinal neuroimaging in the adult zebrafish.

Journal of cell science·2026

Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells.

Journal of cell science·2026

Adjuvant CDK4/6 inhibitors in early-stage breast cancer: Clinical evidence and considerations for risk stratification and treatment selection.

Cancer·2026

Predictive Value of Preoperative Chest Computed Tomography-Measured Diaphragm Thickness Combined With Pulmonary Function for Postoperative Pulmonary Complications After Anatomic Lung Resection in Elderly Patients With Clinical Stage I Non-Small Cell Lung Cancer.

The American surgeon·2026

Integrated Bulk and Single-Cell Transcriptomic Analyses Identify a Five-Gene Signature Associated With Prognosis and the Tumor Microenvironment in Epstein-Barr Virus-Associated Gastric Cancer.

Genetics research·2026

Brain Network Convergence of Abnormal Gray Matter and Functional Activity of Pathological Dissociative Symptoms.

Psychiatry and clinical neurosciences·2026

SHMT2: a Metabolic and Immune Biomarker of Aggressive Lung Adenocarcinoma.

Journal of visualized experiments : JoVE·2026

Time-dependent predictors of seizure outcome in grade 1-2 glioma-related epilepsy.

Epilepsia·2026

Related Experiment Videos

Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events

Related Concept Videos

EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion.

Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role for beta4 tyrosines 1422 and 1440 in hemidesmosome assembly.

Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle.

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling.

Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.

Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.

Atypical PI3Ks coordinate chemotaxis, signaling dynamics, and multicellular development in Dictyostelium.

Targeted ATAC-see (tATAC-see): A visual assay for target-specific chromatin profiling.

Fine-tuning integrin adhesion, trafficking and signalling through post-translational modification.

Dynamic micropatterning uncovers spatial dynamics of B cell immune synapse formation.

A 3D printable device for non-invasive longitudinal neuroimaging in the adult zebrafish.

Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells.

Adjuvant CDK4/6 inhibitors in early-stage breast cancer: Clinical evidence and considerations for risk stratification and treatment selection.

Predictive Value of Preoperative Chest Computed Tomography-Measured Diaphragm Thickness Combined With Pulmonary Function for Postoperative Pulmonary Complications After Anatomic Lung Resection in Elderly Patients With Clinical Stage I Non-Small Cell Lung Cancer.

Integrated Bulk and Single-Cell Transcriptomic Analyses Identify a Five-Gene Signature Associated With Prognosis and the Tumor Microenvironment in Epstein-Barr Virus-Associated Gastric Cancer.

Brain Network Convergence of Abnormal Gray Matter and Functional Activity of Pathological Dissociative Symptoms.

SHMT2: a Metabolic and Immune Biomarker of Aggressive Lung Adenocarcinoma.

Time-dependent predictors of seizure outcome in grade 1-2 glioma-related epilepsy.

Related Experiment Videos

Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events

Related Concept Videos

Related Articles