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Short communication: the use of sodium ironedetate (Sytron) as an MRI rectal contrast agent
1Department of Radiology, Royal Naval Hospital Haslar, Gosport, UK.
Abstract:
The use of bowel contrast medium in abdominal and pelvic MRI examinations is increasingly being recognized as a useful adjunct. A contrast agent which produces a negative contrast effect with T2 weighted (T2W) sequences might help distinguish bowel pathology, which has increased signal intensity, from bowel content. A solution of 7.6 mg ml-1 of sodium ironedetate (Sytron, Link Pharmaceuticals) produces positive contrast on the first (proton density) echo and negative contrast (signal void) on the second (T2W) echo of a dual echo sequence at 0.5 T. When administered rectally it provides a negative contrast bowel marker for pelvic examinations.
Insights
A new bowel contrast agent, sodium ironedetate, aids abdominal and pelvic MRI. It creates a negative contrast effect on T2-weighted images, helping differentiate bowel pathology from normal content.
Area of Science:
- Radiology
- Medical Imaging
- Gastroenterology
Background:
- Abdominal and pelvic MRI increasingly utilizes bowel contrast agents.
- Distinguishing bowel pathology from content is crucial for accurate diagnosis.