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[Non-palpable prostatic cancer. Cure with adenomectomy?]
J Cambronero Santos1, V Carrero López, F J Ortiz Vico
1Servicio de Urología, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid.
Actas Urologicas Espanolas
|April 1, 1996
Summary
Prostate cancer (PC) diagnosis can be challenging. This case study shows a patient with high prostate-specific antigen (PSA) levels and negative biopsies achieved recovery after prostate adenoma removal.
Area of Science:
- Urology
- Oncology
- Diagnostic Imaging
Background:
- Prostate cancer (PC) diagnosis relies on rectal exams, prostate-specific antigen (PSA) tests, and transrectal ultrasounds.
- Increasingly sophisticated diagnostic tools aid in detecting tumors previously undetectable by palpation.
Observation:
- A male patient presented with significantly elevated PSA levels, indicative of metastatic disease.
- Despite high PSA, rectal examinations were normal, and three prostate biopsies yielded negative results.
- A high clinical suspicion for PC persisted despite inconclusive diagnostic tests.
Findings:
- The patient underwent adenomectomy (prostate surgery).
- Post-adenomectomy, PSA levels normalized, remaining below 3 ng/ml at 22-month follow-up.
- Histopathological examination after surgery confirmed the PC diagnosis.
Implications:
- This case suggests that prostate adenoma removal alone may lead to a "recovery" in select PC cases.
- Further investigation is warranted to understand the mechanism of PSA normalization after adenomectomy in such scenarios.
- The findings highlight the complexity of PC diagnosis and the potential for unexpected treatment outcomes.