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Beta 1-adrenoceptor autoimmunity in cardiomyopathy
Y Magnusson1, A Hjalmarson, J Hoebeke
1Wallenberg Laboratory, Sahlgren's Hospital, University of Gothenburg, Sweden.
International Journal of Cardiology
|May 1, 1996
Abstract:
A growing body of studies have confirmed that autoantibodies against beta 1-adrenoceptors are present in different types of cardiomyopathy. This suggests that they play a role in the pathophysiology of the disease. This article will review the data indicating the presence of anti-beta 1-adrenoceptor autoantibodies in cardiomyopathy. It will focus upon their structural and functional properties which could explain their possible role in the induction and development of cardiomyopathic diseases.