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Serum lidocaine concentrations after subcutaneous administration in patients undergoing cardiac catheterization in a
S C Cassidy1, P R Jones, S Cox
1Department of Pediatrics, Ohio State University, Columbus, USA.
The Journal of Pediatrics
|September 1, 1996
Abstract
Objective:
We wished to determine serum lidocaine concentrations after subcutaneous injection during cardiac catheterization.
Method:
Serum lidocaine concentrations were measured in 50 patients during catheterization.
Results:
Serum concentration was linearly related to dose per kilogram of body weight. Lidocaine concentrations were therapeutic in 38% of patients.
Conclusion:
Lidocaine dose must be considered when the drug is used for local anesthesia in children.