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Failure to unwind causes cancer. Genome stability
1Imperial Cancer Research Fund Laboratories, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Current Biology : CB
|March 1, 1996
Abstract:
The recent cloning of the gene defective in individuals with Bloom's syndrome has revealed a link between DNA helicases, genetic instability and a predisposition to cancer.