Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Limb-sparing procedures: postoperative planar bone scan appearance

S C Kaste1, B N Rao, W M Meyer

  • 1Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Pediatric Radiology
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of a pediatric surgical oncology fellowship in a pediatric cancer institution.

Pediatric blood & cancer·2017
Same author

Long-term outcomes of pediatric and adolescent mediastinal germ cell tumors: a single pediatric oncology institutional experience.

Pediatric surgery international·2016
Same author

Long-term functional outcomes and quality of life in adult survivors of childhood extremity sarcomas: a report from the St. Jude Lifetime Cohort Study.

Journal of cancer survivorship : research and practice·2016
Same author

Guidewire Catheter Exchange in Pediatric Oncology: Indications, Postoperative Complications, and Outcomes.

Pediatric blood & cancer·2016
Same author

Bilateral internal hemipelvectomy for osteosarcoma in a pediatric patient previously treated for rhabdomyosarcoma.

Orthopaedics & traumatology, surgery & research : OTSR·2015
Same author

Recurrent osteosarcoma with a single pulmonary metastasis: a multi-institutional review.

British journal of cancer·2014

Postoperative technetium-99m-labeled methylene diphosphonate (99mTc-MDP) bone scans in limb-sparing surgery show normalization of uptake in nearly half of patients. However, persistent abnormal avidity limits their use in detecting complications.

Area of Science:

  • Orthopedic oncology
  • Nuclear medicine
  • Radiology

Background:

  • Limb-sparing surgery is a common treatment for bone tumors.
  • Postoperative assessment of these procedures is crucial for patient outcomes.
  • Technetium-99m-labeled methylene diphosphonate (99mTc-MDP) scintigraphy is used to evaluate bone healing and detect complications.

Purpose of the Study:

  • To evaluate the postoperative scintigraphic appearance of limb-sparing procedures using 99mTc-MDP.
  • To assess the utility of bone scans in identifying complications after limb-sparing surgery for bone tumors.

Main Methods:

  • Retrospective review of medical records and bone scans of patients who underwent limb-sparing surgery.
  • Subjective and semiquantitative assessment of planar bone scans.

Related Experiment Videos

  • Analysis of scintigraphic findings in relation to postoperative complications.

    • Main Results:

    • Nearly half (44%) of patients showed normal 99mTc-MDP tracer avidity at the operative site during follow-up (median 12 months).
    • Nine patients (20%) had normal avidity on their initial follow-up bone scans (median 6 months).
    • Bone scans accurately identified lesions in 8 out of 12 (67%) complications or injuries.

    Conclusions:

    • Many patients exhibit abnormal 99mTc-MDP avidity post-limb-sparing surgery, but uptake normalizes in almost half over time.
    • Persistent abnormal avidity on planar bone scans can hinder the detection of postoperative complications.
    • The use of planar bone scans for primary tumor site assessment postoperatively is limited.