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Related Experiment Videos

Viral oncogenesis and cell cycle control

P Jansen-Dürr1

  • 1Deutsches Krebsforschungszentrum, Forschungsschwerpunkt, Angewandte Tumorvirologie, Heidelberg, Germany.

Virus Research
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Oncogenic viruses hijack cell cycle regulators to promote cancer. Viral oncoproteins override normal cell controls, interfering with signal pathways and inactivating tumor suppressors to drive uncontrolled cell proliferation.

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Area of Science:

  • Oncology
  • Molecular Biology
  • Virology

Background:

  • Cell cycle regulatory genes are crucial in mammalian tumorigenesis.
  • Oncogenic viruses contribute significantly to human cancers, often by providing growth stimuli.
  • Viral oncogenes can override cellular controls that regulate cell cycle progression.