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Resistive training increases insulin action in postmenopausal women
A S Ryan1, R E Pratley, A P Goldberg
1Department of Medicine, University of Maryland at Baltimore, USA.
Summary
Resistive training (RT) improves insulin sensitivity and reduces high insulin levels in postmenopausal women. This exercise may help prevent insulin resistance and type 2 diabetes.
Area of Science:
- Endocrinology
- Exercise Physiology
- Metabolic Health
Background:
- Postmenopausal women are at increased risk for metabolic dysfunction.
- Insulin resistance and impaired glucose metabolism are common in this demographic.
Purpose of the Study:
- To investigate the effects of 4 months of resistive training (RT) on glucose metabolism and insulin sensitivity in postmenopausal women.
- To compare RT alone versus RT with weight loss (RT & WL).
Main Methods:
- Thirteen moderately obese postmenopausal women (50-65 years) underwent hyperglycemic clamps before and after interventions.
- Participants were assigned to RT alone or RT & WL groups.
Main Results:
- RT significantly improved strength in all subjects.
- RT & WL reduced body weight, fat mass, and body fat percentage.
- Insulin response decreased by 29% overall, with a greater reduction in the RT & WL group.
Conclusions:
- Resistive training, with or without weight loss, enhances insulin action and lowers hyperinsulinemia in postmenopausal women.
- RT may help prevent insulin resistance, glucose intolerance, and type 2 diabetes in this population.