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Hormone therapy and phytoestrogens

L L Lien1, E J Lien

  • 1Department of Pharmaceutical Sciences, USC School of Pharmacy, Los Angeles 90033, USA.

Journal of Clinical Pharmacy and Therapeutics
|April 1, 1996
PubMed
Summary

Hormone therapy (HT) can help menopausal women manage symptoms like hot flashes and bone loss. This review examines HT

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Area of Science:

  • Endocrinology
  • Gerontology
  • Pharmacology

Background:

  • Aging leads to decreased sex hormone levels in both men and women.
  • Declining testosterone in men impacts strength, bone density, and libido.
  • Menopause in women involves irregular periods, vaginal dryness, hot flashes, and increased risk of osteoporosis and cardiovascular disease due to estrogen deficiency.

Purpose of the Study:

  • To review the effects of hormone therapy (HT) in menopausal women.
  • To present clinical data on interventions for bone loss, including calcium, HT, and exercise.
  • To compare different HT products and examine alternative therapies.

Main Methods:

  • Review of current clinical data on bone loss interventions.
  • Discussion of the effects of oral and transdermal estrogen therapy (OT) on serum lipids.
  • Comparison of commercially available HT products (indications, dosages, contraindications, side effects, drug interactions).
  • Examination of alternative therapies including Chinese traditional herbs and phytoestrogens.

Main Results:

  • Data on the efficacy of calcium supplementation, HT, and exercise in preventing bone loss are presented.
  • Effects of different estrogen therapy routes on serum lipids are discussed.
  • A comparison of HT products and alternative therapies is provided.

Conclusions:

  • Hormone therapy is a key treatment for menopausal symptoms and associated health risks.
  • Exercise and calcium supplementation can complement HT in managing bone health.
  • Alternative therapies, including phytoestrogens, offer other options for symptom management.

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