[Acid RNAase activity of lysosomes in different regions of rat brain during learning]

Establishment of a defence conditioned reflex in rats raised the level of total activity of acid RNAse (after treatment of the brain tissue with 0.1% Triton X-100) of lysosome-enriched fractions (LEF) in cerebral cortex and subcortical areas. This increase in the enzyme activity was higher in the Krushinsky-Molodkina rats than in Wistar those. The trained animals had a lower than control release of the acid RNAse from the brain cortex lysosomes under effect of the hiotone addition.